MLPA: 10 questions and answers
MLPA: Q&A MLPA is acronym for Multiplex Ligation Probe Amplification, which is a special molecular technique based on PCR. It is used to scan large deletions/duplications/multiplications which are not detectable by standard sequencing (either NGS or Sanger). The alternative to this technique is the qPCR (quantitative PCR). Is it necessary to always perform MLPA? No, it isn’t always indicated. Multiplex