Assisted Reproductive Technology (ART) and neurodevelopmental disorders: is there an association?

Another hot question for Geneticists, Andrologists and Gynecologists: does Assisted Reproductive Technology (ART) increase the risk for neurodevelopmental disorders in newborns? The common conception is that, especially when doing Intra-Cytoplasmic Sperm Injection (ICSI), the natural barriers are skipped by the technology and abnormal germline cells (sperm or oocytes) that would be normally depleted, for instance […]

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Genetic testing in recurrent pregnancy loss: when and which

Of all the clinically recognized pregnancies, about 15% end in a miscarriage, making this event one of the most common adverse events. Unfortunately, about 2-5% of couples take on recurrent pregnancy loss (RPL). However, "Recurrent pregnancy loss" definition, which according to the European Society of Human Reproduction and Embryology is the presence of two or […]

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Genomic imprinting: 10 questions and 10 answers

An epigenetic event Genomic imprinting, although very studied, has many dark sides, even among healthcare professionals. Here are 10 frequently asked questions with relative answers on this phenomenon. 1. What is genomic imprinting? Genomic imprinting is an epigenetic process that modifies the DNA molecule without changing its nucleotide sequence. Regulator mechanisms of imprinting are not […]

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