p.Gly2019Ser: the common LRRK2 mutation
LRRK2 p.Gly2019Ser Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of inherited Parkinson’s disease (PD), and also a risk factor for idiopathic PD. The LRRK2 missense mutation p.Gly2019Ser, which causes the substitution of a glycine with a serine at codon 2019 of the amino acidic chain, is the most common LRRK2 mutation. The penetrance of this mutation is