hereditary diffuse gastric cancer

Gastric cancer

HEREDITARY AND SPORADIC: THE GENETICS Hereditary diffuse gastric cancer is an autosomal dominant cancer predisposition syndrome. In addition to gastric cancer, up to 60% of female mutation carriers develop lobular carcinoma of the breast, and some carriers may develop colorectal cancer. Hereditary diffuse gastric cancer (HDGC) and lobular breast cancer (LBC) are caused by heterozygous

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