CNVs: non-homologous recombination
January 18 2016
During DNA synthesis To further deepen the topic of CNVs formation: beyond evolution, we’ll now go into non-homologous recombination. Non-homologous recombination is a DNA repair mechanism which is not based on homology principles. There are two types of non-homologous recombination: replicative and non-replicative. Non-homologous recombination is the basis of non-recurrent CNVs. Most pathogenic microduplications and microdeletions are rare non-recurrent CNVs. Non-recurrent CNVs are: preferentially located
