Gliomas
THE BIOMARKERS Glioma is the most frequent tumor of the central nervous system in adults. Mutations in IDH genes (IDH1 and IHD2) can be found in more than 70% of low-grade gliomas and in some instances of glioblastoma. As the most frequent mutation, IDH1 Arg132His (also known as R132H) has been served as a predictive marker